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Technology Process of Rimeporide

Rimeporide

Base Information
  • Chemical Name:Rimeporide
  • CAS No.:187870-78-6
  • Molecular Formula:C11H15 N3 O5 S2
  • Molecular Weight:333.389
  • Hs Code.:
  • UNII:QH6B4V5743
  • DSSTox Substance ID:DTXSID30870177
  • Wikipedia:Rimeporide
  • Wikidata:Q21098945
  • NCI Thesaurus Code:C87601
  • Metabolomics Workbench ID:153763
  • ChEMBL ID:CHEMBL2107802
  • Mol file:187870-78-6.mol
Rimeporide

Synonyms:EMD 87580;EMD-87580;EMD87580;N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine;N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine hydrochloride

Suppliers and Price of Rimeporide
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Sigma-Aldrich
  • EMD-87580 ≥98% (HPLC)
  • 5mg
  • $ 113.00
  • Sigma-Aldrich
  • EMD-87580 ≥98% (HPLC)
  • 25mg
  • $ 455.00
  • DC Chemicals
  • Rimeporide(EMD-87580) >98%
  • 1 g
  • $ 2500.00
  • CSNpharm
  • Rimeporide
  • 1mg
  • $ 162.00
  • ChemScene
  • Rimeporide 98.77%
  • 5mg
  • $ 390.00
  • ChemScene
  • Rimeporide 98.77%
  • 1mg
  • $ 190.00
  • Ambeed
  • N-Carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide 99%
  • 5mg
  • $ 415.00
  • aablocks
  • Rimeporide 98%
  • 5mg
  • $ 469.00
Total 10 raw suppliers
Chemical Property of Rimeporide
Chemical Property:
  • PSA：167.50000 
  • LogP:2.96170 
  • Storage Temp.:-20°C 
  • XLogP3:-0.3
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:3
  • Exact Mass:333.04531293
  • Heavy Atom Count:21
  • Complexity:638
Purity/Quality:

98%,99%, *data from raw suppliers

EMD-87580 ≥98% (HPLC) *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=CC(=C(C=C1C(=O)N=C(N)N)S(=O)(=O)C)S(=O)(=O)C
  • Recent ClinicalTrials:Rimeporide in Patients With Duchenne Muscular Dystrophy
  • Recent EU Clinical Trials:A phase Ib, open label study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending oral doses of Rimeporide in patients with Duchenne Muscular Dystrophy
  • Uses EMD-87580 has been used as a selective and potent sodium-hydrogen antiporter 1 (NHE-1) inhibitor in cardiac ventricular myocytes to test its effect on the hypertrophic response.
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