Technology Process of Ethyl-3-acetyl-4-(benzyloxy)-1,2-dihydro-5-methoxy-3H,6H-pyrrolo<3,2-e>indol-7-carboxylat
There total 16 articles about Ethyl-3-acetyl-4-(benzyloxy)-1,2-dihydro-5-methoxy-3H,6H-pyrrolo<3,2-e>indol-7-carboxylat which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 99 percent / K2CO3, KI / dimethylformamide / 1.5 h / 80 °C
2: 80 percent / hydrogen / 5 percent Pd/C / tetrahydrofuran / 10 h / Ambient temperature
3: 1.) NaNO2, HCl, 2.) NaOH, 3.) HCCOH / 1.) H2O, 0 deg C, 2.) H2O/EtOH, 3 h, 10 deg C; 8 h, room temperature, 3.) 75 deg C, 5 h
With
hydrogenchloride; sodium hydroxide; hydrogen; potassium carbonate; potassium iodide; hydroxy acetylene; sodium nitrite;
palladium on activated charcoal;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/hlca.19890720717
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 82 percent / 100 percent HNO3, Ac2O / 0.67 h / 0 °C
2: 89 percent / NaOH / ethanol / 1 h / 10 °C
3: 99 percent / K2CO3, KI / dimethylformamide / 1.5 h / 80 °C
4: 80 percent / hydrogen / 5 percent Pd/C / tetrahydrofuran / 10 h / Ambient temperature
5: 1.) NaNO2, HCl, 2.) NaOH, 3.) HCCOH / 1.) H2O, 0 deg C, 2.) H2O/EtOH, 3 h, 10 deg C; 8 h, room temperature, 3.) 75 deg C, 5 h
With
hydrogenchloride; sodium hydroxide; hydrogen; nitric acid; acetic anhydride; potassium carbonate; potassium iodide; hydroxy acetylene; sodium nitrite;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.1002/hlca.19890720717
