3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine

Base Information

Chemical Name:3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine
CAS No.:906007-12-3
Molecular Formula:C₄₃H₆₂N₆O₁₅Si
Molecular Weight:931.082
Hs Code.:

Synonyms:3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine

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Chemical Property of 3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine

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Technology Process of 3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine

There total 1 articles about 3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 906007-11-2
1-azido-17-(4'-bromomethyl-2'-methoxy-5'-nitrophenoxy)-3,6,9,12,15-pentaoxaheptadecane

: 235744-89-5
5'-O-(tert-butyldimethylsilyl)-(N₃-benzoyl)thymidine

: 906007-12-3
3'-O-[4''-(17'''-azido-3''',6''',9''',12''',15'''-pentaoxaheptadecan-1'''-oxy)-5''-methoxy-2''-nitrophenylmethyl]-5'-O-(tert-butyldimethylsilyl)-3-N-benzoylthymidine

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydroxide; sodium iodide; In chloroform; at 25 ℃; for 12h;
DOI:10.1016/j.bmcl.2006.05.035