Technology Process of 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,2,4-dioxo-,(1alpha,5alpha,6alpha)-(9CI)
There total 2 articles about 3-Oxabicyclo[3.1.0]hexane-6-carboxylicacid,2,4-dioxo-,(1alpha,5alpha,6alpha)-(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic anhydride;
In
acetic acid;
for 2h;
Reflux;
Large scale reaction;
DOI:10.1021/op200174k
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydroxide / ethanol / 50 °C / Reflux; Large scale reaction
2: acetic anhydride / acetic acid / 2 h / Reflux; Large scale reaction
With
acetic anhydride; sodium hydroxide;
In
ethanol; acetic acid;
DOI:10.1021/op200174k
- Guidance literature:
-
(1R,5S,6s)-2,4-dioxo-3-oxabicyclo[3.1.0]hexane-6-carboxylic acid; benzylamine;
With
triethylamine;
In
acetone;
at 20 ℃;
for 3h;
Large scale reaction;
With
sodium acetate; acetic anhydride;
for 1h;
Reflux;
Large scale reaction;
DOI:10.1021/op200174k