triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate

Base Information

• Chemical Name: triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate
• CAS No.: 1346555-73-4
• Molecular Formula: C₆H₁₅N*C₁₃H₈ClN₃O₂
• Molecular Weight: 374.87
• Mol file: 1346555-73-4.mol

Synonyms:triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate

Chemical Property of triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate

There total 1 articles about triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(E)-3-(2-chlorophenyl)-2-cyanoacrylamide (15804-58-7) + 1-cyanoacetyl-3,5-dimethylpyrazole (36140-83-7) → triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate (1346555-73-4)

Guidance literature:

With triethylamine; In acetone; at 10 - 15 ℃;

DOI:10.1007/s10593-011-0855-4

Reference yield: 69.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate (1346555-73-4) + benzylamine (100-46-9) → triethylammonium salt of 7-benzyl-9-(2-chlorophenyl)-2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile (1427290-47-8)

Guidance literature:

In ethanol; water; at 20 ℃; for 1h; Reflux;

DOI:10.1007/s10593-013-1200-x

Reference yield: 59.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate (1346555-73-4) + phenethylamine (64-04-0) → 9-(2-chlorophenyl)-2,4-dioxo-7-(2-phenylethyl)-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile (1427290-48-9)

Guidance literature:

formaldehyd; triethylammonium 4-(2-chlorophenyl)-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridin-2-olate; phenethylamine; In ethanol; water; at 25 ℃; for 48h; Reflux;

With hydrogenchloride; In ethanol; water; for 48h; pH=2;

DOI:10.1007/s10593-013-1200-x

upstream raw materials:

(E)-3-(2-chlorophenyl)-2-cyanoacrylamide

1-cyanoacetyl-3,5-dimethylpyrazole

Downstream raw materials:

triethylammonium salt of 7-benzyl-9-(2-chlorophenyl)-2,4-dioxo-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile

9-(2-chlorophenyl)-2,4-dioxo-7-(2-phenylethyl)-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarbonitrile