1-benzyloxyallenyllithium

Base Information

• Chemical Name: 1-benzyloxyallenyllithium
• CAS No.: 852210-43-6
• Molecular Formula: C₁₀H₉LiO
• Molecular Weight: 152.122
• Mol file: 852210-43-6.mol

Synonyms:1-benzyloxyallenyllithium

Chemical Property of 1-benzyloxyallenyllithium

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-benzyloxyallenyllithium

There total 1 articles about 1-benzyloxyallenyllithium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzyloxyallene (67515-49-5) → 1-benzyloxyallenyllithium (852210-43-6)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -40 ℃;

DOI:10.1021/ol0260573

Reference yield: 75.0%

N-methoxy-N-methylacetamide lithium enolate + pentacarbonyl[(4-chlorophenyl)(methoxy)carbene]chromium(0) + 1-benzyloxyallenyllithium (852210-43-6) → 4-(p-chlorophenyl)-5-deuterio-3-deuteriomethyl-2,4-dimethoxycyclopent-2-enone

Guidance literature:

N-methoxy-N-methylacetamide lithium enolate; pentacarbonyl[(4-chlorophenyl)(methoxy)carbene]chromium⁽⁰⁾; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere; Schlenk technique;

1-benzyloxyallenyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 12.75h; regioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201404670

Reference yield: 75.0%

N-methoxy-N-methylacetamide lithium enolate + pentacarbonyl(1-methoxybenzylidene)chromium(0) (27436-93-7) + 1-benzyloxyallenyllithium (852210-43-6) → 2-(benzyloxy)-4-methoxy-3-methyl-4-phenylcyclopent-2-enone

Guidance literature:

N-methoxy-N-methylacetamide lithium enolate; pentacarbonyl(1-methoxybenzylidene)chromium⁽⁰⁾; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere; Schlenk technique;

1-benzyloxyallenyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 12.75h; regioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201404670

upstream raw materials:

1-benzyloxyallene

Downstream raw materials:

(3S,4'S)-2-benzyl-4-benzyloxy-3-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)-3,6-dihydro-2H-1,2-oxazine