Technology Process of C21H19NO4S
There total 5 articles about C21H19NO4S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
diethyl ether;
at -78 ℃;
for 4.5h;
DOI:10.1039/c2ob25842k
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium hydride / tetrahydrofuran / 15 h / 0 - 20 °C
2: diisobutylaluminium hydride / diethyl ether / 4.5 h / -78 °C
With
sodium hydride; diisobutylaluminium hydride;
In
tetrahydrofuran; diethyl ether;
DOI:10.1039/c2ob25842k
- Guidance literature:
-
Multi-step reaction with 4 steps
1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; caesium carbonate / toluene / 40 h / Reflux
2: palladium diacetate; potassium carbonate; Trimethylacetic acid / 14 h / 115 °C
3: sodium hydride / tetrahydrofuran / 15 h / 0 - 20 °C
4: diisobutylaluminium hydride / diethyl ether / 4.5 h / -78 °C
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium hydride; diisobutylaluminium hydride; potassium carbonate; caesium carbonate; Trimethylacetic acid;
In
tetrahydrofuran; diethyl ether; toluene;
1: Buchwald-Hartwig coupling;
DOI:10.1039/c2ob25842k