α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol

Base Information

• Chemical Name: α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol
• CAS No.: 87757-02-6
• Molecular Formula: C₂₁H₂₄FN₃O₂
• Molecular Weight: 369.439
• Mol file: 87757-02-6.mol

Synonyms:α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol

Chemical Property of α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol

There total 2 articles about α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

4-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>-1-(4-fluorophenyl)-1-butanone (87692-12-4) → α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol (87757-02-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 20h;

DOI:10.1021/jm00153a010

Reference yield:

4-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>-1-(4-fluorophenyl)-1-butanone hydrochloride (87692-13-5) → α-<3-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>propyl>-4-fluorobenzenemethanol (87757-02-6)

Guidance literature:

With sodium borohydrid; In ethanol;

upstream raw materials:

4-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>-1-(4-fluorophenyl)-1-butanone

4-<4-(1,2-benzisoxazol-3-yl)-1-piperazinyl>-1-(4-fluorophenyl)-1-butanone hydrochloride