6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

Base Information

Chemical Name:6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione
CAS No.:1562523-07-2
Molecular Formula:C₁₂H₁₀F₃N₃O₃
Molecular Weight:301.225
Hs Code.:

Synonyms:6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

Suppliers and Price of 6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

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Technology Process of 6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

There total 3 articles about 6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1562523-07-2
6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

Guidance literature:: With palladium 10% on activated carbon; hydrogen; acetic acid; In methanol; for 1.5h; under 2585.81 Torr;

Reference yield:

: 1562523-18-5
6-(benzyloxy)-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

: 1562523-07-2
6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 1h; under 155.149 Torr;
DOI:10.1021/acs.jmedchem.5b00482

Reference yield:

: 1562523-14-1
6-bromo-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

: 1562523-07-2
6-hydroxy-2-(3-(trifluoromethyl)phenethyl)-1,2,4-triazine-3,5-(2H,4H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / 150 °C

2: hydrogen; palladium 10% on activated carbon / methanol / 1 h / 20 °C / 155.15 Torr

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In methanol;
DOI:10.1021/acs.jmedchem.5b00482