NH₂-L-Tyr(OBut)-Bu

Base Information

• Chemical Name: NH₂-L-Tyr(OBut)-Bu
• CAS No.: 479414-01-2
• Molecular Formula: C₁₇H₂₈N₂O₂
• Molecular Weight: 292.422
• Mol file: 479414-01-2.mol

Synonyms:NH₂-L-Tyr(OBut)-Bu

Chemical Property of NH₂-L-Tyr(OBut)-Bu

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of NH₂-L-Tyr(OBut)-Bu

There total 3 articles about NH₂-L-Tyr(OBut)-Bu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-L-Tyr(OBut)-Bu (403641-27-0) → NH2-L-Tyr(OBut)-Bu (479414-01-2)

Guidance literature:

With piperidine; In dichloromethane; at 22 ℃; for 2h;

DOI:10.1021/ja0122849 DOI:10.1021/ja021081x

Reference yield:

Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) → NH2-L-Tyr(OBut)-Bu (479414-01-2)

Guidance literature:

Multi-step reaction with 2 steps

1: EDC / CH₂Cl₂; butan-1-ol / 4 h / 22 °C

2: 4.50 g / piperidine / CH₂Cl₂ / 2 h / 22 °C

With piperidine; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; butan-1-ol;

DOI:10.1021/ja021081x

Reference yield:

Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) → NH2-L-Tyr(OBut)-Bu (479414-01-2)

Guidance literature:

Multi-step reaction with 2 steps

1: HOBt; EDC / CH₂Cl₂ / 4 h / 22 °C

2: 4.50 g / piperidine / CH₂Cl₂ / 2 h / 22 °C

With piperidine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane;

DOI:10.1021/ja0122849

upstream raw materials:

Fmoc-L-Tyr(OBut)-Bu

Fmoc-Tyr(tBu)-OH

Downstream raw materials:

NH₂-L-Tle-L-Tyr(OBut)-Bu