(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER

Base Information

Chemical Name:(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER
CAS No.:186586-71-0
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
Mol file:186586-71-0.mol

Synonyms:(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER;H-BETA-ME-L-PRO-OET;L-Proline, 3-methyl-, ethyl ester, (3R)- (9CI)

Suppliers and Price of (2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER 95.00%
5MG
$ 497.87

Total 2 raw suppliers

Chemical Property of (2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER

Chemical Property:

PSA：38.33000
LogP:0.87630

Purity/Quality:

97% ^*data from raw suppliers

(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER

There total 2 articles about (2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186586-70-9
(2S,3R)-3-Methyl-1-((S)-1-phenyl-ethyl)-pyrrolidine-2-carboxylic acid ethyl ester

: 186586-71-0
(2S,3R)-3-Methyl-pyrrolidine-2-carboxylic acid ethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; Yield given;
DOI:10.1016/S0040-4039(96)02221-6

Reference yield:

: 186586-65-2
[but-3-enyl-((S)-1-phenyl-ethyl)amino]acetic acid ethyl ester

: 186586-71-0
(2S,3R)-3-Methyl-pyrrolidine-2-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LDA, ZnBr₂; 2.) aq. ammonium chloride / 1.) Et₂O, -90 deg C to r.t., 20 min

2: hydrogen / Pd/C

With ammonium chloride; hydrogen; zinc dibromide; lithium diisopropyl amide; palladium on activated charcoal;
DOI:10.1016/S0040-4039(96)02221-6