(1R,2R)-3-chloro-1-phenylpropane-1,2-diol

Base Information

Chemical Name:(1R,2R)-3-chloro-1-phenylpropane-1,2-diol
CAS No.:1137968-48-9
Molecular Formula:C₉H₁₁ClO₂
Molecular Weight:186.638
Hs Code.:

Synonyms:(1R,2R)-3-chloro-1-phenylpropane-1,2-diol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2R)-3-chloro-1-phenylpropane-1,2-diol

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Technology Process of (1R,2R)-3-chloro-1-phenylpropane-1,2-diol

There total 2 articles about (1R,2R)-3-chloro-1-phenylpropane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 2687-12-9
cinnamyl chloride

: 1137968-48-9
(1R,2R)-3-chloro-1-phenylpropane-1,2-diol

Guidance literature:: With potassium osmate(VI) dihydrate; methanesulfonamide; water; potassium carbonate; 1,4-bis(9-O-dihydroquinidine)phthalazine; potassium hexacyanoferrate(III); In tert-butyl alcohol; at 20 ℃; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/jo8026998

Reference yield: 43.0%

: 4392-27-2,66982-43-2,125411-08-7,145164-91-6
trans-2-(chloromethyl)-3-phenyloxirane

: 184046-30-8
trans-2-(chloromethyl)-3-phenyloxirane

: 1137968-48-9
(1R,2R)-3-chloro-1-phenylpropane-1,2-diol

Guidance literature:: With Epoxide hydrolase Kau₂ from Escherichia coli RE₃; In aq. phosphate buffer; tert-butyl methyl ether; at 27 ℃; pH=7; enantioselective reaction; Resolution of racemate;
DOI:10.1002/adsc.201401164