1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

Base Information

Chemical Name:1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one
CAS No.:111249-10-6
Molecular Formula:C₁₆H₁₅NO₃S
Molecular Weight:301.366
Hs Code.:

1-(2,2-Dioxo-2,3-dihydro-2λ<sup>6</sup>-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

Synonyms:1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

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Chemical Property of 1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

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Technology Process of 1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

There total 3 articles about 1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 25145-43-1,36240-11-6,59981-93-0,22414-26-2
2-phenylpropionyl chloride

: 111248-89-6
1,3-dihydro-2,1-benzisothiazole 2,2-dioxide

: 111249-10-6
1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

Guidance literature:: With pyridine; at 0 ℃; for 3h;

Reference yield:

: 89665-79-2
(2-chlorophenyl)-methanesulfonamide

: 111249-10-6
1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / potassium carbonate, copper-bronze powder / various solvent(s) / 3 h / 180 °C

2: 76 percent / pyridine / 3 h / 0 °C

With pyridine; copper; potassium carbonate; In various solvent(s);

Reference yield:

: 111249-29-7
2-aminobenzylsulfonic acid sodium salt

: 111249-10-6
1-(2,2-Dioxo-2,3-dihydro-2λ⁶-benzo[c]isothiazol-1-yl)-2-phenyl-propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 36 percent / POCl₃ / 3 h / 170 °C

2: 76 percent / pyridine / 3 h / 0 °C

With pyridine; trichlorophosphate;