(2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride

Base Information

• Chemical Name: (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride
• CAS No.: 443360-68-7
• Molecular Formula: C₁₁H₈ClNO₃
• Molecular Weight: 237.642
• Mol file: 443360-68-7.mol

Synonyms:(2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride

Chemical Property of (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride

There total 3 articles about (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2E,4E)-5-(4-nitrophenyl)penta-2,4-dienoic acid (92356-78-0) → (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride (443360-68-7)

Guidance literature:

With oxalyl dichloride; In benzene;

Reference yield:

(2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoic acid methyl ester (92356-68-8) → (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride (443360-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / ethanol / 4 h

2: (COCl)2 / benzene / Heating

With potassium hydroxide; oxalyl dichloride; In ethanol; benzene;

Reference yield:

4-nitrobenzaldehdye (555-16-8) → (2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoyl chloride (443360-68-7)

Guidance literature:

Multi-step reaction with 3 steps

2: 1) alkali, 2) acid

3: oxalyl chloride / benzene

With oxalyl dichloride; In benzene;

upstream raw materials:

(2E,4E)-5-(4-nitrophenyl)penta-2,4-dienoic acid

(2E,4E)-5-(4-Nitro-phenyl)-penta-2,4-dienoic acid methyl ester

4-nitrobenzaldehdye

Downstream raw materials:

(2E,4E)-5-(4-Nitro-phenyl)-1-piperidin-1-yl-penta-2,4-dien-1-one