N₁-(1,1-dimethylethyl)-N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide

Base Information

• Chemical Name: N₁-(1,1-dimethylethyl)-N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide
• CAS No.: 281197-76-0
• Molecular Formula: C₃₀H₄₀N₆O₂
• Molecular Weight: 516.687

Synonyms:N₁-(1,1-dimethylethyl)-N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide

Chemical Property of N₁-(1,1-dimethylethyl)-N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide

Chemical Property:

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Technology Process of N₁-(1,1-dimethylethyl)-N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide

There total 2 articles about N₁-(1,1-dimethylethyl)-N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

N2-[3-(1H-imidazol-1-yl)propyl]-N2,4-bis(phenylmethyl)-1,2(R)-piperazinecarboxamide (281197-79-3) + Tert-butyl isocyanate (1609-86-5) → N1-(1,1-dimethylethyl)-N2-[3-(1H-imidazol-1-yl)propyl]-N2,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide (281197-76-0)

Guidance literature:

In dichloromethane; at 20 ℃;

Reference yield: 83.0%

→ N1-(1,1-dimethylethyl)-N2-[3-(1H-imidazol-1-yl)propyl]-N2,4-bis(phenylmethyl)-1,2(R)-piperazinedicarboxamide (281197-76-0)

Guidance literature:

upstream raw materials:

N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinecarboxamide

Tert-butyl isocyanate

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