m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

Base Information

Chemical Name:m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride
CAS No.:87545-85-5
Molecular Formula:C₁₈H₁₅N₃O₂S*2ClH
Molecular Weight:410.324
Hs Code.:

Synonyms:m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

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Chemical Property of m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

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Technology Process of m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

There total 3 articles about m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87545-86-6
3-tert-Butoxycarbonylamino-propionic acid 3-benzo[d]imidazo[2,1-b]thiazol-2-yl-phenyl ester

: 87545-85-5
m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; at 60 - 70 ℃; Yield given;
DOI:10.1016/0223-5234(88)90205-X

Reference yield:

: β-(N-tert-butoxycarbonyl)alanine

: 79889-39-7
2-(m-hydroxyphenyl)imidazo<2,1-b>benzothiazole

: 2-[m-[β-(N-tert-butoxycarbonyl)alanyl]phenyl]imidazo[2,1-b]benzothiazole

: 87545-85-5
m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

Guidance literature:

Reference yield:

: 79889-39-7
2-(m-hydroxyphenyl)imidazo<2,1-b>benzothiazole

: 87545-85-5
m-(2-imidazo[2,1-b]benzothiazolyl)phenyl-3-aminopropionate dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: DCC / pyridine / 3 h / 20 - 25 °C

2: 2n HCl / ethanol / 60 - 70 °C

With hydrogenchloride; dicyclohexyl-carbodiimide; In pyridine; ethanol;
DOI:10.1016/0223-5234(88)90205-X