7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride

Base Information

• Chemical Name: 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride
• CAS No.: 855121-60-7
• Molecular Formula: C₁₇H₉Cl₄NO
• Molecular Weight: 385.077
• Mol file: 855121-60-7.mol

Synonyms:7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride

Chemical Property of 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride

There total 3 articles about 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chloroisatin (6341-92-0) → 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride (855121-60-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic KOH

2: SOCl₂

With potassium hydroxide; thionyl chloride;

DOI:10.1021/ja01213a041

Reference yield:

7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carboxylic acid (854871-43-5) → 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride (855121-60-7)

Guidance literature:

With thionyl chloride;

DOI:10.1021/ja01213a041

Reference yield:

2-methyl-4,5-dichloroacetophenone (53803-91-1) → 7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carbonyl chloride (855121-60-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic KOH

2: SOCl₂

With potassium hydroxide; thionyl chloride;

DOI:10.1021/ja01213a041

upstream raw materials:

7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-quinoline-4-carboxylic acid

6-chloroisatin

2-methyl-4,5-dichloroacetophenone

Downstream raw materials:

1-[7-chloro-2-(4,5-dichloro-2-methyl-phenyl)-[4]quinolyl]-2-diazo-ethanone