2-Phenyl-3-(2-thienyl)propanoic acid

Base Information

Chemical Name:2-Phenyl-3-(2-thienyl)propanoic acid
CAS No.:51535-43-4
Molecular Formula:C13H12 O2 S
Molecular Weight:232.303
Hs Code.:
NSC Number:39228
DSSTox Substance ID:DTXSID50284833
Mol file:51535-43-4.mol

Synonyms:51535-43-4;2-phenyl-3-(thiophen-2-yl)propanoic acid;2-Phenyl-3-(2-thienyl)propanoic acid;NSC39228;ChemDiv2_002265;Oprea1_868236;DTXSID50284833;SRDHAZNTMXQYGM-UHFFFAOYSA-N;HMS1375G21;NSC-39228;STK674855;AKOS005593636;NCGC00332306-01;2-Phenyl-3-(2-thienyl)propanoic acid #;2-Thiophenylpropanoic acid, ,.gamma.-phenyl-;Propionic acid, 2-phenyl-3-(2-thiophenyl)-;AB01326147-02;SR-01000522290;SR-01000522290-1

Suppliers and Price of 2-Phenyl-3-(2-thienyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Phenyl-3-(2-thienyl)propanoic acid

Chemical Property:

Vapor Pressure:2.46E-05mmHg at 25°C
Boiling Point:344.7°Cat760mmHg
Flash Point:162.3°C
Density:1.26g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:232.05580079
Heavy Atom Count:16
Complexity:236

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CC2=CC=CS2)C(=O)O

Technology Process of 2-Phenyl-3-(2-thienyl)propanoic acid

There total 6 articles about 2-Phenyl-3-(2-thienyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: (Z)-2-Phenyl-3-thiophen-2-yl-acrylic acid

: 51535-43-4
2-phenyl-3-(thiophen-2-yl)propanoic acid

Guidance literature:: With C₄₂H₄₈CoP₂; hydrogen; triethylamine; zinc; In methanol; at 50 ℃; for 16h; under 25858.1 Torr; enantioselective reaction;
DOI:10.1021/jacs.9b13876

Reference yield:

: 51535-44-5
phenyl-[2]thienylmethyl-malonic acid diethyl ester

: 51535-43-4
2-phenyl-3-(thiophen-2-yl)propanoic acid

Guidance literature:: With alkaline solution; Behandeln des Reaktionsprodukts mit wss. Salzsaeure;
DOI:10.1021/ja01214a019

Reference yield:

: 28744-77-6
sodium diethyl-2-phenylmalonate

: 51535-43-4
2-phenyl-3-(thiophen-2-yl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol

2: aq.-ethanolic alkaline solution / Behandeln des Reaktionsprodukts mit wss. Salzsaeure

With ethanol; alkaline solution;
DOI:10.1021/ja01214a019