2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine

Base Information

Chemical Name:2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine
CAS No.:185346-20-7
Molecular Formula:C₂₅H₂₃N₃O₂
Molecular Weight:397.477
Hs Code.:
European Community (EC) Number:633-753-4
Nikkaji Number:J1.339.516K
Wikidata:Q76416027
Mol file:185346-20-7.mol

Synonyms:185346-20-7;2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine;2,6-Bis((4S,5S)-4-methyl-5-phenyl-4,5-dihydrooxazol-2-yl)pyridine;(4S,5S)-4-methyl-2-[6-[(4S,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]pyridin-2-yl]-5-phenyl-4,5-dihydro-1,3-oxazole;2 6-Bis[(4s 5s)-4-methyl-5-phenyl-2-oxa&;SCHEMBL918209;WAQJMWVRZVOTCH-ZCVTWQBDSA-N;AKOS025394477;CS-0064054;J-011891;2,6-Bis[(4S)-4beta-methyl-5alpha-phenyl-2-oxazoline-2-yl]pyridine;2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine, 98%

Suppliers and Price of 2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine 98%
500mg
$ 252.00

Arctom
2,6-Bis((4S,5S)-4-methyl-5-phenyl-4,5-dihydrooxazol-2-yl)pyridine 98%
1g
$ 644.00

Arctom
2,6-Bis((4S,5S)-4-methyl-5-phenyl-4,5-dihydrooxazol-2-yl)pyridine 98%
250mg
$ 261.00

Arctom
2,6-Bis((4S,5S)-4-methyl-5-phenyl-4,5-dihydrooxazol-2-yl)pyridine 98%
100mg
$ 155.00

American Custom Chemicals Corporation
2,6-BIS[(4S,5S)-4-METHYL-5-PHENYL-2-OXAZOLINYL]PYRIDINE 95.00%
500MG
$ 762.83

Total 4 raw suppliers

Chemical Property of 2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:138-141 °C(lit.)
Refractive Index:1.655
Boiling Point:600.6°Cat760mmHg
PKA:3.39±0.70(Predicted)
Flash Point:317.1°C
PSA：56.07000
Density:1.25g/cm³
LogP:3.76600
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:397.17902698
Heavy Atom Count:30
Complexity:597

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1C(OC(=N1)C2=NC(=CC=C2)C3=NC(C(O3)C4=CC=CC=C4)C)C5=CC=CC=C5
Isomeric SMILES:C[C@H]1[C@@H](OC(=N1)C2=NC(=CC=C2)C3=N[C@H]([C@@H](O3)C4=CC=CC=C4)C)C5=CC=CC=C5

Technology Process of 2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine

There total 3 articles about 2,6-Bis[(4S,5S)-4-methyl-5-phenyl-2-oxazolinyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: Pyridine-2,6-dicarboxylic acid bis-[((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-amide]

: 185346-20-7
2,6-bis[(4S,5S)-4,5-dihydro-4-methyl-5-phenyl-2-oxazolyl]pyridine

Guidance literature:: With boron trifluoride diethyl etherate; at 120 ℃; for 1.5h;
DOI:10.1021/jo9616264

Reference yield:

: 37577-28-9,58550-13-3,757124-50-8
(1S,2R)-(+)-norphedrine

: 55309-58-5
pyridine-2,6-dicarboximidic acid dimethyl ester

: 185346-20-7
2,6-Bis-((4R,5S)-4-methyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-pyridine

Guidance literature:: In dichloromethane; for 48h; Heating;
DOI:10.1016/j.tetlet.2005.05.019

Reference yield:

: 2893-33-6
pyridine-2,6-dinitrile

: 185346-20-7
2,6-Bis-((4R,5S)-4-methyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOCH₃ / 36 h / 20 °C

2: CH₂Cl₂ / 48 h / Heating

With sodium methylate; In dichloromethane;
DOI:10.1016/j.tetlet.2005.05.019