Ethyl 6H-1,2-oxazine-3-carboxylate

Base Information

Chemical Name:Ethyl 6H-1,2-oxazine-3-carboxylate
CAS No.:185223-40-9
Molecular Formula:C₇H₉NO₃
Molecular Weight:155.153
Hs Code.:
DSSTox Substance ID:DTXSID80449534
Nikkaji Number:J1.159.087J
Wikidata:Q82269042
Mol file:185223-40-9.mol

Synonyms:185223-40-9;Ethyl 6H-oxazine-3-carboxylate;Ethyl 6H-1,2-oxazine-3-carboxylate;6H-1,2-Oxazine-3-carboxylicacid,ethylester(9CI);DTXSID80449534;6H-1,2-OXAZINE-3-CARBOXYLIC ACID ETHYL ESTER

Suppliers and Price of Ethyl 6H-1,2-oxazine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 6H-1,2-oxazine-3-carboxylate

Chemical Property:

PSA：47.89000
LogP:-0.07250
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:155.058243149
Heavy Atom Count:11
Complexity:208

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=NOCC=C1

Technology Process of Ethyl 6H-1,2-oxazine-3-carboxylate

There total 3 articles about Ethyl 6H-1,2-oxazine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 118653-61-5
(E)-ethyl 2-oxo-3-pentenoate

: 185223-40-9
6H-[1,2]Oxazine-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 25 percent / N-bromosuccinimide, 2,2'-azobisisobutyronitrile / CCl₄ / 5 h / Heating

2: NH₂OH*HCl / CHCl₃; methanol / 4 h / Ambient temperature

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); hydroxylamine hydrochloride; In methanol; tetrachloromethane; chloroform;
DOI:10.1016/0040-4020(96)00909-X

Reference yield:

: 185223-34-1
(E)-5-Bromo-2-oxo-pent-3-enoic acid ethyl ester

: (E)-5-Bromo-2-[(Z)-hydroxyimino]-pent-3-enoic acid ethyl ester

: 185223-40-9
6H-[1,2]Oxazine-3-carboxylic acid ethyl ester

Guidance literature:: With hydroxylamine hydrochloride; In methanol; chloroform; for 4h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1016/0040-4020(96)00909-X

Reference yield:

: 185223-34-1
(E)-5-Bromo-2-oxo-pent-3-enoic acid ethyl ester

: 185223-40-9
6H-[1,2]Oxazine-3-carboxylic acid ethyl ester

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; Yield given. Multistep reaction; 1.) CHCl₃, MeOH, RT, 4 h, 2.) DMF, RT, 30 min;
DOI:10.1016/0040-4020(96)00909-X