5H-Cyclopenta[c]pyridin-5-ol,6,7-dihydro-7-methyl-,trans-(9CI)

Base Information

• Chemical Name: 5H-Cyclopenta[c]pyridin-5-ol,6,7-dihydro-7-methyl-,trans-(9CI)
• CAS No.: 185067-10-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.192
• Mol file: 185067-10-1.mol

Synonyms:5H-Cyclopenta[c]pyridin-5-ol,6,7-dihydro-7-methyl-, trans- (9CI)

Chemical Property of 5H-Cyclopenta[c]pyridin-5-ol,6,7-dihydro-7-methyl-,trans-(9CI)

Chemical Property:

• PSA: 33.12000
• LogP: 1.62220

Purity/Quality:

99% ^*data from raw suppliers

(5R,7R)-rel-6,7-dihydro-7-methyl-5H-Cyclopenta[c]pyridin-5-ol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5H-Cyclopenta[c]pyridin-5-ol,6,7-dihydro-7-methyl-,trans-(9CI)

There total 12 articles about 5H-Cyclopenta[c]pyridin-5-ol,6,7-dihydro-7-methyl-,trans-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-bromo-4-(1'-hydroxy-3'-butenyl)pyridine (184827-08-5) → Leptorhabin (55727-36-1,119365-15-0,185067-06-5,185067-10-1)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 110 ℃; for 3h; Yield given;

DOI:10.1016/0040-4039(96)01822-9

Reference yield:

3-bromo-4-(1'-hydroxy-3'-butenyl)pyridine (184827-08-5) → 6,7-dihydro-7-methyl-5H-[2]pyrindin-5-ol (119365-15-0,185067-06-5,185067-10-1) + 6,7-dihydro-7-methyl-5H-[2]pyrindin-5-ol (119365-15-0,185067-06-5,185067-10-1)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 110 ℃; for 3h; Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(99)00999-0

Reference yield:

3-bromo-4-(1'-hydroxy-3'-butenyl)pyridine (184827-08-5) → 6,7-dihydro-7-methyl-5H-[2]pyrindin-5-ol (119365-15-0,185067-06-5,185067-10-1) + 6,7-dihydro-7-methyl-5H-[2]pyrindin-5-ol (119365-15-0,185067-06-5,185067-10-1)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; at 110 ℃; for 3h; Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(99)00999-0

upstream raw materials:

3-bromo-4-(1'-hydroxy-3'-butenyl)pyridine

3-bromo-pyridine-4-carbaldehyde

pyridine-4-carbaldehyde

3-Bromopyridine