4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

Base Information

Chemical Name:4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide
CAS No.:1398045-37-8
Molecular Formula:C₂₆H₂₆F₄N₄O₂S
Molecular Weight:534.578
Hs Code.:

Synonyms:4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

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Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

There total 3 articles about 4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1311158-94-7
C₉H₂F₄N₂S

: 1398047-56-7
C₁₇H₂₅N₃O

: 1398045-37-8
4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

Guidance literature:: C₉H₂F₄N₂S; C₁₇H₂₅N₃O; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; methanol; In N,N-dimethyl-formamide; for 2h; Reflux;

Reference yield:

: 1398047-50-1
C₁₈H₂₈N₂O₃

: 1398045-37-8
4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride / ethyl acetate / 2 h

1.2: 1 h / 0 - 20 °C

2.1: zinc(II) chloride / 3 h / 20 °C

3.1: N,N-dimethyl-formamide / 20 °C

3.2: 2 h / Reflux

With hydrogenchloride; zinc(II) chloride; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 1146975-35-0
C₁₃H₂₀N₂O

: 1398045-37-8
4-{4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-phenyl}-2,2,N-trimethyl-butyramide

Guidance literature:: Multi-step reaction with 2 steps

1.1: zinc(II) chloride / 3 h / 20 °C

2.1: N,N-dimethyl-formamide / 20 °C

2.2: 2 h / Reflux

zinc(II) chloride; In N,N-dimethyl-formamide;