L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Base Information

Chemical Name:L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride
CAS No.:124456-05-9
Molecular Formula:C₃₇H₅₁N₅O₆*ClH
Molecular Weight:698.303
Hs Code.:

Synonyms:L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Suppliers and Price of L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

There total 13 articles about L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 98908-42-0
N-(tert-bytyloxycarbonyl)-L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester

: 124456-05-9
L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;

Reference yield:

: 13734-41-3
t-Boc-L-valine

: 124456-05-9
L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) DCC, 2.) 4-ethylmorpholine / 1.) CH₂Cl₂, 0 deg C, 40 min, 2.) CH₂Cl₂, a) 0 deg C, 4 h, b) RT, overnight

2: 4 M aq. NaOH / methanol / 1 h / Ambient temperature

3: TEA / CH₂Cl₂ / 0.5 h / -15 °C

4: TEA / CH₂Cl₂ / -10 - 20 °C

5: 72 percent / 4 M HCl / dioxane / 1 h / Ambient temperature

With N-ethylmorpholine;; hydrogenchloride; sodium hydroxide; TEA; dicyclohexyl-carbodiimide; In 1,4-dioxane; methanol; dichloromethane;

Reference yield:

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 124456-05-9
L-valyl-L-prolyl-L-leucyl-L-phenylalanyl-L-proline benzyl ester hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: TEA / CHCl₃ / 0.5 h / -20 °C

2: TEA / CHCl₃ / a) -20 deg C, 2 h, b) RT, overnight

3: TEA / CH₂Cl₂ / -10 - 20 °C

4: 72 percent / 4 M HCl / dioxane / 1 h / Ambient temperature

With hydrogenchloride; TEA; In 1,4-dioxane; dichloromethane; chloroform;