2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene

Base Information

• Chemical Name: 2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene
• CAS No.: 171291-29-5
• Molecular Formula: C₁₆H₂₇I
• Molecular Weight: 346.295
• Mol file: 171291-29-5.mol

Synonyms:2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene

Chemical Property of 2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene

There total 2 articles about 2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(E)-4-Methyl-6-(2',6',6'-trimethyl-1'-cyclohexenyl)hex-3-en-1-ol (110202-07-8) → 2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene (171291-29-5)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/jo0268097

Reference yield:

C16H29Al → 2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene (171291-29-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 12.85 g / CH₂Cl₂; heptane / 12 h / -23 - 20 °C

2: 92 percent / triphenylphosphine; imidazole; iodine / CH₂Cl₂ / 2 h / 20 °C

With 1H-imidazole; iodine; triphenylphosphine; In n-heptane; dichloromethane;

DOI:10.1021/jo0268097

Reference yield: 66.0%

2-[(E)-6-iodo-3-methylhex-3-enyl]-1,3,3-trimethylcyclohexene (171291-29-5) + (-)-(2R)-5'-triethylsilyl-5-tributylstannanyl-2,3-dihydro[2,3']bifuranyl → (+)-(1R)-(3Z,7E)-4-iodo-8-methyl-1-(5'-triethylsilylfuran-3'-yl)-10-(2'',6'',6''-trimethylcyclohex-1-enyl)deca-3,7-dien-1-ol (539802-71-6)

Guidance literature:

Multistep reaction;

DOI:10.1021/jo0268097

upstream raw materials:

(E)-4-Methyl-6-(2',6',6'-trimethyl-1'-cyclohexenyl)hex-3-en-1-ol

Downstream raw materials:

(E)-2-((R)-3-Furan-3-yl-3-hydroxy-propionyl)-6-methyl-8-(2,6,6-trimethyl-cyclohex-1-enyl)-oct-5-enoic acid methyl ester

(+)-(1R)-(3Z,7E)-4-iodo-8-methyl-1-(5'-triethylsilylfuran-3'-yl)-10-(2'',6'',6''-trimethylcyclohex-1-enyl)deca-3,7-dien-1-ol

(+)-(R)-manoalide

(+)-(6R)-3-[(E)-4'-methyl-6'-(2'',6'',6''-trimethylcyclohex-1''-enyl)hex-3'-enyl]-6-(5'''-triethylsilylfuran-3'''-yl)-5,6-dihydropyran-2-one