ethyl 1-iodobutyl-2-oxocyclohexanoate

Base Information

• Chemical Name: ethyl 1-iodobutyl-2-oxocyclohexanoate
• CAS No.: 110528-47-7
• Molecular Formula: C₁₃H₂₁IO₃
• Molecular Weight: 352.212
• Mol file: 110528-47-7.mol

Synonyms:ethyl 1-iodobutyl-2-oxocyclohexanoate

Chemical Property of ethyl 1-iodobutyl-2-oxocyclohexanoate

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 1-iodobutyl-2-oxocyclohexanoate

There total 1 articles about ethyl 1-iodobutyl-2-oxocyclohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1,4-Diiodobutane (628-21-7) + ethyl 2-oxocyclohexane carboxylate (1655-07-8) → ethyl 1-iodobutyl-2-oxocyclohexanoate (110528-47-7)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydride; In tetrahydrofuran; for 6h; Ambient temperature;

DOI:10.1016/0040-4020(89)80035-3

Reference yield: 71.0%

ethyl 1-iodobutyl-2-oxocyclohexanoate (110528-47-7) → ethyl 2-butylcyclohexanone-2-carboxylate (66709-51-1) + ethyl cyclodecanone-6-carboxylate (110528-48-8)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; Heating;

DOI:10.1021/ja00255a071

Reference yield: 71.0%

ethyl 1-iodobutyl-2-oxocyclohexanoate (110528-47-7) → ethyl 2-butylcyclohexanone-2-carboxylate (66709-51-1) + Ethyl 5-oxocyclodecane-1-carboxylate (129104-53-6)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 48h; Heating;

DOI:10.1016/0040-4020(89)80035-3

upstream raw materials:

1,4-Diiodobutane

ethyl 2-oxocyclohexane carboxylate

Downstream raw materials:

ethyl 2-butylcyclohexanone-2-carboxylate

Ethyl 5-oxocyclodecane-1-carboxylate

ethyl cyclodecanone-6-carboxylate