2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Base Information

Chemical Name:2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester
CAS No.:516490-74-7
Molecular Formula:C₁₈H₂₃NO₅
Molecular Weight:333.384
Hs Code.:

Synonyms:2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Suppliers and Price of 2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

There total 3 articles about 2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 42487-19-4
(2,5-dimethoxyphenyl)ethylamine

: 277751-23-2
(+/-)-cyclopent-2-ene-1,2-dicarboxylic acid 1-methyl ester

: 516490-74-7
2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Guidance literature:: With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 65 ℃; for 16h;
DOI:10.1021/jm021065a

Reference yield:

: 516490-53-2
2-but-3-enyl-3-methylenesuccinic acid 1-methyl ester

: 516490-74-7
2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / second-generation Grubbs' catalyst / CH₂Cl₂ / 40 h / 40 °C

2: 43 percent / DIPEA; bis(2-oxo-3-oxazolidinyl)phosphinic chloride / dimethylformamide / 16 h / 65 °C

With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm021065a

Reference yield:

: 102-56-7,102526-87-4
2,5-dimethoxyaniline

: 516490-74-7
2-[(2,5-dimethoxyphenyl)ethylcarbamoyl]cyclopent-2-enecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / 4 A molecular sieves; pyridine-borane / methanol / 14 h

2: 43 percent / DIPEA; bis(2-oxo-3-oxazolidinyl)phosphinic chloride / dimethylformamide / 16 h / 65 °C

With 4 A molecular sieve; bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; borane pyridine complex; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm021065a