(E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate

Base Information

• Chemical Name: (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate
• CAS No.: 1332865-01-6
• Molecular Formula: C₁₈H₂₆N₂O₃
• Molecular Weight: 318.416
• Mol file: 1332865-01-6.mol

Synonyms:(E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate

Chemical Property of (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate

There total 5 articles about (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(E)-(tert-butyl) 1-(5-(benzyloxy)-3-methylpent-2-enyl)hydrazinecarboxylate (1332864-70-6) → (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate (1332865-01-6)

Guidance literature:

With iodosylbenzene; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1021/ja2066219

Reference yield:

(E)-ethyl 5-(benzyloxy)-3-methylpent-2-enoate (1332864-56-8) → (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate (1332865-01-6)

Guidance literature:

Multi-step reaction with 4 steps

1: diisobutylaluminium hydride / tetrahydrofuran; hexane / -78 - 20 °C / Inert atmosphere

2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3: ethylenediamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

4: iodosylbenzene / tetrahydrofuran / 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; iodosylbenzene; diisobutylaluminium hydride; ethylenediamine; triphenylphosphine; In tetrahydrofuran; hexane;

DOI:10.1021/ja2066219

Reference yield:

C26H26Cl4N2O5 (1332864-69-3) → (E)-(tert-butyl) 2-(5-(benzyloxy)-3-methylpent-1-en-3-yl)diazenecarboxylate (1332865-01-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ethylenediamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2: iodosylbenzene / tetrahydrofuran / 20 °C / Inert atmosphere

With iodosylbenzene; ethylenediamine; In tetrahydrofuran;

DOI:10.1021/ja2066219

upstream raw materials:

(E)-(tert-butyl) 1-(5-(benzyloxy)-3-methylpent-2-enyl)hydrazinecarboxylate

(E)-ethyl 5-(benzyloxy)-3-methylpent-2-enoate

C₂₆H₂₆Cl₄N₂O₅

(E)-5-(benzyloxy)-3-methylpent-2-en-1-ol