(R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate
CAS No.:1140496-43-0
Molecular Formula:C₂₂H₂₃ClN₄O₂
Molecular Weight:410.903
Hs Code.:

Synonyms:(R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

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Chemical Property of (R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

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Technology Process of (R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

There total 1 articles about (R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 18871-66-4
N,N-dimethylacetamide dimethyl acetal

: 1140496-39-4
4-chlorobenzyl-hydrazine acetate

: 62937-47-7,58274-22-9
(2R)-2-carbamoyl-pyrrolidine-1-carboxylic acid benzyl ester

: 1140496-43-0
(R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

Guidance literature:: N,N-dimethylacetamide dimethyl acetal; (2R)-2-carbamoyl-pyrrolidine-1-carboxylic acid benzyl ester; at 120 ℃; for 2h;

4-chlorobenzyl-hydrazine acetate; With acetic acid; at 90 ℃; for 1.5h;

Reference yield: 31.0%

: 1140496-43-0
(R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate

: 1140496-44-1
(R)-1-(4-chlorobenzyl)-3-methyl-5-(pyrrolidin-2-yl)-1H-1,2,4-triazole

Guidance literature:: (R)-benzyl 2-(2-(4-chlorobenzyl)-5-methyl-2H-1,2,4-triazol-3-yl)pyrrolidine-1-carboxylate; With trimethylsilyl iodide; In dichloromethane; at 0 - 20 ℃; for 1h;

With methanol; In dichloromethane; at 20 ℃; for 0.25h;

With hydrogenchloride; sodium hydroxide; more than 3 stages;