[(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

Base Information

Chemical Name:[(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester
CAS No.:871700-12-8
Molecular Formula:C₂₃H₃₀N₂O₃
Molecular Weight:382.503
Hs Code.:

Synonyms:[(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

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Chemical Property of [(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

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Technology Process of [(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

There total 1 articles about [(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 99-88-7
4-Isopropylaniline

: 30925-08-7
N-tert-butoxycarbonyl-N-methylphenylglycine

: 871700-12-8
[(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

Guidance literature:: With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 22 ℃; for 2h;
DOI:10.1124/mol.105.010959

Reference yield: 98.0%

: 871700-12-8
[(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

: 853139-07-8
N-(4-isopropyl-phenyl)-2-methylamino-2-phenyl-acetamide

Guidance literature:: With trifluoroacetic acid; at 22 ℃; for 0.25h;
DOI:10.1124/mol.105.010959

Reference yield:

: 871700-12-8
[(4-isopropylphenylcarbamoyl)phenylmethyl]methylcarbamic acid tert-butyl ester

: PG-01

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / trifluoroacetic acid / 0.25 h / 22 °C

2: 92 percent / 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide; 4-(N,N-dimethylamino)pyridine / CH₂Cl₂ / 2 h / 22 °C

With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; In dichloromethane;
DOI:10.1124/mol.105.010959