1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine

Base Information

• Chemical Name: 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine
• CAS No.: 933063-95-7
• Molecular Formula: C₄₂H₄₃N₃O₁₀
• Molecular Weight: 749.818

Synonyms:1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine

Chemical Property of 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine

There total 3 articles about 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1-{2-O-[(3-acetoxypropoxy)methyl]-β-D-ribofuranosyl}-N4-benzoylcytosine (933063-87-7) + mono-4-methoxytrityl chloride (14470-28-1) → 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N4-benzoylcytosine (933063-95-7)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1135/cccc20060804

Reference yield:

1-{2-O-[(3-acetoxypropoxy)methyl]-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl}-N4-benzoylcytosine (933063-83-3) → 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N4-benzoylcytosine (933063-95-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / Bu₄NF*3H₂O / tetrahydrofuran / 20 °C

2: 77 percent / pyridine / 20 °C

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1135/cccc20060804

Reference yield:

3-(hydroxymethoxy)propan-1-ol diacetate (93185-18-3) → 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N4-benzoylcytosine (933063-95-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / tin tetrachloride / 1,2-dichloro-ethane / 0.33 h / -12 °C

2: 89 percent / Bu₄NF*3H₂O / tetrahydrofuran / 20 °C

3: 77 percent / pyridine / 20 °C

With pyridine; tetrabutyl ammonium fluoride; tin(IV) chloride; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1135/cccc20060804

upstream raw materials:

1-{2-O-[(3-acetoxypropoxy)methyl]-β-D-ribofuranosyl}-N⁴-benzoylcytosine

mono-4-methoxytrityl chloride

1-{2-O-[(3-acetoxypropoxy)methyl]-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine

3-(hydroxymethoxy)propan-1-ol diacetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 933063-95-7 1-{2-O-[(3-acetoxypropoxy)methyl]-5-O-(4-methoxytrityl)-β-D-ribofuranosyl}-N⁴-benzoylcytosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send