1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol

Base Information

• Chemical Name: 1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol
• CAS No.: 870672-95-0
• Molecular Formula: C₂₆H₃₇NO₇
• Molecular Weight: 475.582
• Mol file: 870672-95-0.mol

Synonyms:1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol

Chemical Property of 1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol

There total 1 articles about 1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1,2,5,6-di-O-cyclohexylidene-D-mannitol (76779-67-4) + p-Tolylisocyanate (622-58-2,374675-64-6) → 1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol (870672-95-0)

Guidance literature:

With dmap; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.tetasy.2005.08.040

Reference yield: 43.0%

1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol (870672-95-0) + [(R)-1,1'-binaphthyl-2,2'-diyl]chlorophosphite → p-tolyl-carbamic acid 2-(3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalen-4-yloxy)-1,2-bis-(1,4-dioxa-spiro[4.5]dec-2-yl)-ethyl ester

Guidance literature:

With dmap; triethylamine; In toluene; at 0 - 20 ℃;

DOI:10.1016/j.tetasy.2005.08.040

Reference yield: 43.0%

1,2:5,6-di-O-cyclohexylidene-3-O-[(4-methyl)phenylcarbamoyl]-D-mannitol (870672-95-0) + [(R)-1,1'-binaphthyl-2,2'-diyl]chlorophosphite → C46H48O9NP

Guidance literature:

DOI:10.1016/j.tetasy.2007.07.008

upstream raw materials:

1,2,5,6-di-O-cyclohexylidene-D-mannitol

p-Tolylisocyanate