methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

Base Information

Chemical Name:methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate
CAS No.:865137-73-1
Molecular Formula:C₂₄H₂₃ClN₂O₆S
Molecular Weight:502.975
Hs Code.:

Synonyms:methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

Suppliers and Price of methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

There total 2 articles about methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 865137-72-0
methyl 3-(4-{[(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

: 16473-35-1
4-(hydroxymethyl)benzyl chloride

: 865137-73-1
methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

Guidance literature:: methyl 3-(4-{[(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate; 4-(hydroxymethyl)benzyl chloride; With triphenylphosphine; In toluene; at 0 ℃;

With diethylazodicarboxylate; In toluene; at 20 ℃; for 72h;

Reference yield:

: 2393-17-1
3-(4-aminophenyl)propionic acid

: 865137-73-1
methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / 0.17 h / 0 °C

1.2: 18 h / 20 °C

2.1: pyridine / 45 h / 20 °C

3.1: triphenylphosphine / toluene / 0 °C

3.2: 72 h / 20 °C

With pyridine; thionyl chloride; triphenylphosphine; In toluene;

Reference yield: 32.0%

: 948-65-2
2-phenyl-indole

: 865137-73-1
methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate

: methyl 3-[4-([(2-nitrophenyl)sulfonyl]{4-[(2-phenyl-1H-indol-3-yl)methyl]benzyl}amino)phenyl]propanoate

Guidance literature:: 2-phenyl-indole; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

methyl 3-(4-{[4-(chloromethyl)benzyl][(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate; In N,N-dimethyl-formamide; at 20 ℃; for 3h;