(7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate

Base Information

Chemical Name:(7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate
CAS No.:1429197-64-7
Molecular Formula:C₂HF₃O₂*C₂₅H₃₁F₃N₂O₃S
Molecular Weight:610.618
Hs Code.:

Synonyms:(7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate

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Technology Process of (7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate

There total 1 articles about (7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1429196-80-4
(7R,8aS)-2-{[3-(trifluoromethyl)phenyl]sulfonyl}octahydropyrrolo[1,2-a]-pyrazin-7-ol

: 18880-00-7
1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

: 76-05-1
trifluoroacetic acid

: 1429197-64-7
(7R,8aS)-7-[(4-tert-butylbenzyl)oxy]-2-{[3-(trifluoromethyl)phenyl]-sulfonyl}octahydropyrrolo[1,2-a]pyrazine trifluoroacetate

Guidance literature:: (7R,8aS)-2-{[3-(trifluoromethyl)phenyl]sulfonyl}octahydropyrrolo[1,2-a]-pyrazin-7-ol; With potassium tert-butylate; In tetrahydrofuran; for 0.166667h;

1-(bromomethyl)-4-(1,1-dimethylethyl)benzene; In tetrahydrofuran; at 20 ℃; for 16h;

trifluoroacetic acid; In water; acetonitrile;