N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride

Base Information

Chemical Name:N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride
CAS No.:1313481-21-8
Molecular Formula:C₂₇H₂₈ClN₃O
Molecular Weight:445.992
Hs Code.:

Synonyms:N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride

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Chemical Property of N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride

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Technology Process of N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride

There total 2 articles about N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86-38-4
6,9-dichloro-2-methoxyacridine

: 68304-96-1
1-(4-METHYLBENZYL)-4-PIPERIDINYLAMINE

: 1313481-21-8
N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride

Guidance literature:: 6,9-dichloro-2-methoxyacridine; 1-(4-METHYLBENZYL)-4-PIPERIDINYLAMINE; In phenol; at 120 ℃; for 4h;

With sodium hydroxide; In phenol;
DOI:10.1016/j.ejmech.2011.04.016

Reference yield:

: 937723-95-0
tert-butyl N-[1-(4-methylbenzyl)-4-piperidinyl]carbamate

: 1313481-21-8
N-(1-(4-methylbenzyl)piperidin-4-yl)-6-chloro-2-methoxyacridin-9-amine dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane

2: phenol / 4 h / 120 °C

With trifluoroacetic acid; In dichloromethane; phenol;
DOI:10.1016/j.ejmech.2011.04.016