C₅₄H₅₀Br₂O₅

Base Information

• Chemical Name: C₅₄H₅₀Br₂O₅
• CAS No.: 225376-60-3
• Molecular Formula: C₅₄H₅₀Br₂O₅
• Molecular Weight: 938.796
• Mol file: 225376-60-3.mol

Synonyms:C₅₄H₅₀Br₂O₅

Chemical Property of C₅₄H₅₀Br₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₄H₅₀Br₂O₅

There total 13 articles about C₅₄H₅₀Br₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4-tri-O-benzyl-6-O-trityl-D-glucopyranose → C54H50Br2O5 (225376-60-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 95 percent / LiAlH₄ / tetrahydrofuran / 4 h / 0 °C

2: 95 percent / Et₃N, DMAP / CH₂Cl₂ / 16 h / Ambient temperature

3: 94 percent / NaH / tetrahydrofuran / 14 h / Heating

4: 97 percent / TBAF / tetrahydrofuran / 4 h / Ambient temperature

5: 89 percent

6: 1.) PPh₃, 2.) Et₃N / 1.) CH₂Cl₂, -20 deg C, 2.) -60 deg c to room temperature; room temperature, 30 min

With dmap; lithium aluminium tetrahydride; tetrabutyl ammonium fluoride; sodium hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo990086i

Reference yield:

2,3,4-tri-O-benzyl-6-O-trityl-D-glucitol (225376-26-1) → C54H50Br2O5 (225376-60-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 95 percent / Et₃N, DMAP / CH₂Cl₂ / 16 h / Ambient temperature

2: 94 percent / NaH / tetrahydrofuran / 14 h / Heating

3: 97 percent / TBAF / tetrahydrofuran / 4 h / Ambient temperature

4: 89 percent

5: 1.) PPh₃, 2.) Et₃N / 1.) CH₂Cl₂, -20 deg C, 2.) -60 deg c to room temperature; room temperature, 30 min

With dmap; tetrabutyl ammonium fluoride; sodium hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo990086i

Reference yield:

(2R,3R,4R,5S)-3,4,5-Tris-benzyloxy-6-(tert-butyl-dimethyl-silanyloxy)-1-trityloxy-hexan-2-ol (225376-34-1) → C54H50Br2O5 (225376-60-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 94 percent / NaH / tetrahydrofuran / 14 h / Heating

2: 97 percent / TBAF / tetrahydrofuran / 4 h / Ambient temperature

3: 89 percent

4: 1.) PPh₃, 2.) Et₃N / 1.) CH₂Cl₂, -20 deg C, 2.) -60 deg c to room temperature; room temperature, 30 min

With tetrabutyl ammonium fluoride; sodium hydride; triethylamine; triphenylphosphine; In tetrahydrofuran;

DOI:10.1021/jo990086i

upstream raw materials:

benzyl bromide

benzyl chloride

1-O-allyl-6-O-trityl-β-D-glucopyranoside

2,3,4-tri-O-benzyl-6-O-trityl-D-glucitol

Downstream raw materials:

(2R,3R,4R,5S)-2,3,4,5-Tetrakis-benzyloxy-8-trimethylsilanyl-oct-6-yn-1-ol

(2S,3S,4R,5S)-2,3,4,5-Tetrakis-benzyloxy-8-trimethylsilanyl-oct-6-ynal

Trimethyl-((4S,5R,6R,7R)-4,5,6,7-tetrakis-benzyloxy-8-trityloxy-oct-2-ynyl)-silane

C₅₄H₅₀O₅