(4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one

Base Information

• Chemical Name: (4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one
• CAS No.: 1059067-82-1
• Molecular Formula: C₁₈H₂₅NO₆
• Molecular Weight: 351.4

Synonyms:(4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one

Chemical Property of (4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one

Chemical Property:

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Technology Process of (4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one

There total 1 articles about (4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H39NO6Si (1059067-97-8) → (4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one (1059067-82-1)

Guidance literature:

C₂₄H₃₉NO₆Si; With water; acetic acid; In tetrahydrofuran; at 20 ℃; for 19h;

With water; sodium hydrogencarbonate; In ethyl acetate;

DOI:10.1021/ol801709c

Reference yield:

(4S,4'R,5'R)-4-benzyloxymethyl-4-(5'-(2''-hydroxyethyl)-2',2'-dimethyl-[1',3']dioxolan-4'-yl)oxazolidin-2-one (1059067-82-1) + 1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → C25H29N5O5S

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 - 40 ℃; Inert atmosphere;

DOI:10.1021/ol801709c

upstream raw materials:

C₂₄H₃₉NO₆Si

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