Technology Process of (4R,5S)-N-Tosyl-4,5-dihydroxy-5-ene-hexylamine
There total 5 articles about (4R,5S)-N-Tosyl-4,5-dihydroxy-5-ene-hexylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; toluene-4-sulfonic acid;
In
methanol; water;
for 0.5h;
Ambient temperature;
DOI:10.1016/S0040-4020(96)01049-6
- Guidance literature:
-
Multi-step reaction with 6 steps
1: L-(+)-DIPT, TBHP, Ti(OiPr)4, molecular sieves 4 Angstroem / CH2Cl2 / 240 h / -20 °C
2: acetone; diethyl ether / 15 h / Ambient temperature
3: 98 percent / p-TSA / CH2Cl2 / Ambient temperature
4: LAH / diethyl ether / 1.5 h / Ambient temperature
5: Et3N / CH2Cl2 / 0.5 h / Ambient temperature
6: 91 percent / p-TSA, HCl / methanol; H2O / 0.5 h / Ambient temperature
With
titanium(IV) isopropylate; hydrogenchloride; tert.-butylhydroperoxide; lithium aluminium tetrahydride; L-(+)-diisopropyl tartrate; 4 A molecular sieve; toluene-4-sulfonic acid; triethylamine;
In
methanol; diethyl ether; dichloromethane; water; acetone;
DOI:10.1016/S0040-4020(96)01049-6
- Guidance literature:
-
Multi-step reaction with 5 steps
1: acetone; diethyl ether / 15 h / Ambient temperature
2: 98 percent / p-TSA / CH2Cl2 / Ambient temperature
3: LAH / diethyl ether / 1.5 h / Ambient temperature
4: Et3N / CH2Cl2 / 0.5 h / Ambient temperature
5: 91 percent / p-TSA, HCl / methanol; H2O / 0.5 h / Ambient temperature
With
hydrogenchloride; lithium aluminium tetrahydride; toluene-4-sulfonic acid; triethylamine;
In
methanol; diethyl ether; dichloromethane; water; acetone;
DOI:10.1016/S0040-4020(96)01049-6
