ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate

Base Information

Chemical Name:ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate
CAS No.:1207618-04-9
Molecular Formula:C₁₈H₂₂N₂O₃S
Molecular Weight:346.45
Hs Code.:

Synonyms:ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate

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Technology Process of ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate

There total 2 articles about ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 675149-01-6
1-thiocarbamoyl-piperidine-4-carboxylic acid ethyl ester

: 51317-87-4
2‐bromo‐1‐(2‐hydroxy‐5‐methylphenyl)ethanone

: 1207618-04-9
ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate

Guidance literature:: In ethanol; at 80 ℃; for 5h;

Reference yield:

: 1207618-04-9
ethyl 1-[4-(2-hydroxy-5-methylphenyl)-1,3-thiazol-2-yl]-4-piperidinecarboxylate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; at 80 ℃; for 16h; Inert atmosphere;