Technology Process of Cyclopentaneacetonitrile, 2,2-dimethyl-3-oxo-, (S)- (9CI)
There total 4 articles about Cyclopentaneacetonitrile, 2,2-dimethyl-3-oxo-, (S)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1,4-dibromo-butane; potassium carbonate;
In
water;
at 125 ℃;
for 0.333333h;
under 375.038 Torr;
Microwave irradiation;
DOI:10.3390/molecules25132978
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydroxylamine hydrochloride; pyridine / ethanol / 10 h / Reflux
2: trifluoroacetic acid / dichloromethane / 16 h / 20 °C
3: potassium carbonate; 1,4-dibromo-butane / water / 0.33 h / 125 °C / 375.04 Torr / Microwave irradiation
With
pyridine; 1,4-dibromo-butane; hydroxylamine hydrochloride; potassium carbonate; trifluoroacetic acid;
In
ethanol; dichloromethane; water;
DOI:10.3390/molecules25132978
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: triethylamine; diphenyl phosphoryl azide / toluene / 3 h / Inert atmosphere; Reflux
1.2: 96 h / Reflux
2.1: hydroxylamine hydrochloride; pyridine / ethanol / 10 h / Reflux
3.1: trifluoroacetic acid / dichloromethane / 16 h / 20 °C
4.1: potassium carbonate; 1,4-dibromo-butane / water / 0.33 h / 125 °C / 375.04 Torr / Microwave irradiation
With
pyridine; 1,4-dibromo-butane; diphenyl phosphoryl azide; hydroxylamine hydrochloride; potassium carbonate; triethylamine; trifluoroacetic acid;
In
ethanol; dichloromethane; water; toluene;
1.1: |Curtius Rearrangement;
DOI:10.3390/molecules25132978
