Technology Process of 4-N-benzoyl-3'-deoxy-3',4'-didehydrocytidine
There total 4 articles about 4-N-benzoyl-3'-deoxy-3',4'-didehydrocytidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: toluene-4-sulfonic acid / N,N-dimethyl-formamide / 20 °C
2: pyridine; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
3: triethylamine / N,N-dimethyl-formamide / Inert atmosphere
4: methanol; sodium tetrahydroborate / N,N-dimethyl-formamide / Cooling with ice
With
pyridine; methanol; sodium tetrahydroborate; toluene-4-sulfonic acid; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid;
In
N,N-dimethyl-formamide;
2: modified Moffat oxidation;
DOI:10.1016/j.tetlet.2010.10.117
- Guidance literature:
-
Multi-step reaction with 3 steps
1: pyridine; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
2: triethylamine / N,N-dimethyl-formamide / Inert atmosphere
3: methanol; sodium tetrahydroborate / N,N-dimethyl-formamide / Cooling with ice
With
pyridine; methanol; sodium tetrahydroborate; dimethyl sulfoxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid;
In
N,N-dimethyl-formamide;
1: modified Moffat oxidation;
DOI:10.1016/j.tetlet.2010.10.117
