Tert-butyl (4-carbamoyloxazol-2-YL)methylcarbamate

Base Information

Chemical Name:Tert-butyl (4-carbamoyloxazol-2-YL)methylcarbamate
CAS No.:182120-97-4
Molecular Formula:C₁₀H₁₅N₃O₄
Molecular Weight:241.247
Hs Code.:
DSSTox Substance ID:DTXSID80700556
Wikidata:Q82631958
Mol file:182120-97-4.mol

Synonyms:182120-97-4;TERT-BUTYL (4-CARBAMOYLOXAZOL-2-YL)METHYLCARBAMATE;tert-Butyl ((4-carbamoyloxazol-2-yl)methyl)carbamate;tert-Butyl [(4-carbamoyl-1,3-oxazol-2-yl)methyl]carbamate;DTXSID80700556;tert-butyl N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]carbamate;AB44767

Suppliers and Price of Tert-butyl (4-carbamoyloxazol-2-YL)methylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-(4-CARBAMOYLOXAZOL-2-YL)METHYLCARBAMATE 95.00%
5MG
$ 499.59

Total 4 raw suppliers

Chemical Property of Tert-butyl (4-carbamoyloxazol-2-YL)methylcarbamate

Chemical Property:

PSA：98.66000
LogP:1.84510
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:241.10625597
Heavy Atom Count:17
Complexity:300

Purity/Quality:

98%min ^*data from raw suppliers

TERT-BUTYL-(4-CARBAMOYLOXAZOL-2-YL)METHYLCARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC1=NC(=CO1)C(=O)N

Technology Process of Tert-butyl (4-carbamoyloxazol-2-YL)methylcarbamate

There total 7 articles about Tert-butyl (4-carbamoyloxazol-2-YL)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 182120-89-4
methyl 2-({[(tert-butoxy)carbonyl]amino}methyl)-1,3-oxazole-4-carboxylate

: 182120-97-4
tert-butyl((4-carbamoyloxazol-2-yl)methyl)carbamate

Guidance literature:: With ammonium hydroxide; In methanol; for 15h; Ambient temperature;

Reference yield:

: 83661-73-8
methyl (tert-butoxycarbonyl)glycyl-L-serinate

: 182120-97-4
tert-butyl((4-carbamoyloxazol-2-yl)methyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: diethylamino-sulfur trifluoride / dichloromethane / -78 °C

1.2: 0 °C

2.1: ammonium hydroxide / methanol / 24 h

With ammonium hydroxide; diethylamino-sulfur trifluoride; In methanol; dichloromethane;
DOI:10.1021/ol102916b

Reference yield:

: 871715-69-4
methyl 2-({[(tert-butoxy)carbonyl]amino}methyl)-4,5-dihydro-1,3-oxazole-4-carboxylate

: 182120-97-4
tert-butyl((4-carbamoyloxazol-2-yl)methyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: DBU, pyridine / acetonitrile; CCl₄ / 3 h / Ambient temperature

2: 96 percent / aq. NH₃ / methanol / 15 h / Ambient temperature

With pyridine; ammonium hydroxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In methanol; tetrachloromethane; acetonitrile;