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2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate

Base Information
  • Chemical Name:2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate
  • CAS No.:182004-65-5
  • Molecular Formula:C17H21N3O6S2
  • Molecular Weight:427.5
  • Hs Code.:
  • European Community (EC) Number:689-434-5
  • DSSTox Substance ID:DTXSID50431360
  • Pharos Ligand ID:3C52PVW99B4Z
  • Mol file:182004-65-5.mol
2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate

Synonyms:2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate;compound No. 7943;KB R7943;KB-7943;KB-R7943;KBR 7943;KBR-7943;KBR7943;No 7943

Suppliers and Price of 2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • KB-R7943 mesylate
  • 10mg
  • $ 423.00
  • TRC
  • KB-R7943Mesylate
  • 1mg
  • $ 45.00
  • TRC
  • KB-R7943Mesylate
  • 2.5mg
  • $ 95.00
  • TRC
  • KB-R7943Mesylate
  • 5mg
  • $ 180.00
  • Tocris
  • KB-R7943mesylate ≥99%(HPLC)
  • 10
  • $ 184.00
  • Tocris
  • KB-R7943mesylate ≥99%(HPLC)
  • 50
  • $ 774.00
  • TCI Chemical
  • S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >98.0%(HPLC)
  • 50mg
  • $ 472.00
  • TCI Chemical
  • S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate >98.0%(HPLC)
  • 10mg
  • $ 137.00
  • Sigma-Aldrich
  • KB-R7943 ≥98% (HPLC), powder
  • 5 mg
  • $ 122.00
  • Sigma-Aldrich
  • KB-R7943 - CAS 182004-65-5 - Calbiochem
  • 5 mg
  • $ 147.00
Total 32 raw suppliers
Chemical Property of 2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate
Chemical Property:
  • Vapor Pressure:1.67E-11mmHg at 25°C 
  • Boiling Point:534.6°Cat760mmHg 
  • Flash Point:277.1°C 
  • PSA:192.97000 
  • Density:g/cm3 
  • LogP:5.25100 
  • Storage Temp.:Store at RT 
  • Solubility.:Soluble in DMSO (up to 50 mg/ml). 
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:8
  • Rotatable Bond Count:7
  • Exact Mass:427.08717775
  • Heavy Atom Count:28
  • Complexity:479
Purity/Quality:

99%, *data from raw suppliers

KB-R7943 mesylate *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CS(=O)(=O)O.C1=CC(=CC=C1CCSC(=N)N)OCC2=CC=C(C=C2)[N+](=O)[O-]
  • Description KB-R7943 (182004-65-5) is a potent and selective inhibitor of the reversed Na+/Ca2+ exchanger (NCE or NCX; IC50‘s = 1.2-2.4 μM in cardiomyocytes, smooth muscle cells, NCX1-transfected fibroblasts1; 0.7 μM in cultured rat forebrain2). KB-R7943 has also been shown to inhibit the mitochondrial Ca2+ uniporter (MCU) Ki = 5.5 μM.3 Recently shown to inhibit complex I in the mitochondrial respiratory chain (IC50 = 11.4 μM) and block NMDA receptors (IC50 = 13.4 μM).4
  • Uses KB-R7943 Mesylate is a selective inhibitor of the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1.
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