3-cyano-2-benzyloxymethanamido propionic acid, methyl ester

Base Information

• Chemical Name: 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester
• CAS No.: 91841-18-8
• Molecular Formula: C₁₃H₁₄N₂O₄
• Molecular Weight: 262.265
• Mol file: 91841-18-8.mol

Synonyms:3-cyano-2-benzyloxymethanamido propionic acid, methyl ester

Chemical Property of 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester

There total 1 articles about 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester (91841-18-8)

Guidance literature:

Carbobenzoxy-β-cyan-DL-alanin, CH2N2;

DOI:10.1021/ja01066a033

Reference yield: 90.0%

trans-[(PPh3)2Pt(CF3)(CH2Cl2)]BF4 (87249-59-0) + 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester (91841-18-8) → Pt(CF3)(P(C6H5)3)2(NCCH2CH(CO2CH3)NHCOOCH2C6H5)(1+)*BF4(1-)=[Pt(CF3)(P(C6H5)3)2(NCCH2CH(CO2CH3)NHCOOCH2C6H5)]BF4 (176900-85-9)

Guidance literature:

In dichloromethane; stirring under N2 for 30 min; evapn., stirring with hexane for 30 min, collection (filtration); elem. anal.;

DOI:10.1016/0020-1693(96)05126-2

Reference yield:

tributyltin azide (17846-68-3) + 3-cyano-2-benzyloxymethanamido propionic acid, methyl ester (91841-18-8) → 3-tetrazolyl-2-benzyloxymethanamido propionic acid, methyl ester

Guidance literature:

With sodium hydroxide; In tetrahydrofuran;

Downstream raw materials:

Pt(CF₃)(P(C₆H₅)3)2(NCCH₂CH(CO₂CH₃)NHCOOCH₂C₆H₅)⁽¹⁺⁾*BF₄^(1-)=[Pt(CF₃)(P(C₆H₅)3)2(NCCH₂CH(CO₂CH₃)NHCOOCH₂C₆H₅)]BF₄