3-Pyridazinamine, 6-(2-naphthalenylthio)-

Base Information

• Chemical Name: 3-Pyridazinamine, 6-(2-naphthalenylthio)-
• CAS No.: 180901-21-7
• Molecular Formula: C₁₄H₁₁N₃S
• Molecular Weight: 253.327
• Mol file: 180901-21-7.mol

Synonyms:3-Pyridazinamine, 6-(2-naphthalenylthio)-

Chemical Property of 3-Pyridazinamine, 6-(2-naphthalenylthio)-

Chemical Property:

• Vapor Pressure: 1.01E-12mmHg at 25°C
• Refractive Index: 1.749
• Boiling Point: 563.5°Cat760mmHg
• Flash Point: 294.6°C
• PSA: 77.10000
• Density: 1.35g/cm³
• LogP: 3.94440

Purity/Quality:

98% ^*data from raw suppliers

6-(2-NAPHTHALENYLTHIO)-3-PYRIDAZINAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridazinamine, 6-(2-naphthalenylthio)-

There total 1 articles about 3-Pyridazinamine, 6-(2-naphthalenylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

6-chloro-pyridazin-3-ylamine (5469-69-2) + 2-Naphthalenethiol (91-60-1) → 6-(Naphthalen-2-ylsulfanyl)-pyridazin-3-ylamine (180901-21-7)

Guidance literature:

With sodium hydroxide; In water; at 153 ℃; for 14h;

DOI:10.1071/ch9960443

Reference yield:

6-(Naphthalen-2-ylsulfanyl)-pyridazin-3-ylamine (180901-21-7) → N-[6-(Naphthalen-2-ylsulfanyl)-2-phenyl-imidazo[1,2-b]pyridazin-3-ylmethyl]-acetamide

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) sodium hydrogen carbonate / 1.) ethanol, reflux, 1 h, 2.) ethanol, reflux, 14 h

2: 32 percent / conc. sulfuric acid / acetic acid / 14 h / 100 °C

With sulfuric acid; sodium hydrogencarbonate; In acetic acid;

DOI:10.1071/ch9960443

Reference yield:

6-(Naphthalen-2-ylsulfanyl)-pyridazin-3-ylamine (180901-21-7) → N-[6-(Naphthalen-2-ylsulfanyl)-2-phenyl-imidazo[1,2-b]pyridazin-3-ylmethyl]-benzamide

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) sodium hydrogen carbonate / 1.) ethanol, reflux, 1 h, 2.) ethanol, reflux, 14 h

2: 41 percent / conc. sulfuric acid / acetic acid / 14 h / Heating

With sulfuric acid; sodium hydrogencarbonate; In acetic acid;

DOI:10.1071/ch9960443

upstream raw materials:

6-chloro-pyridazin-3-ylamine

2-Naphthalenethiol

Refernces