2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid

Base Information

Chemical Name:2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid
CAS No.:733049-29-1
Molecular Formula:C₁₂H₂₀N₂O₅
Molecular Weight:272.301
Hs Code.:
European Community (EC) Number:874-837-2

Synonyms:733049-29-1;2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid;(3-[(TERT-BUTOXYCARBONYL)AMINO]-2-OXOPIPERIDIN-1-YL)ACETIC ACID;{3-[(tert-Butoxycarbonyl)amino]-2-oxopiperidin-1-yl}acetic acid;2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]-2-oxopiperidin-1-yl]acetic acid;2-(3-{[(tert-butoxy)carbonyl]amino}-2-oxopiperidin-1-yl)acetic acid;2-(3-([(TERT-BUTOXY)CARBONYL]AMINO)-2-OXOPIPERIDIN-1-YL)ACETIC ACID;SCHEMBL203869;(S)-2-(3-(tert-Butoxycarbonylamino)-2-oxopiperidin-1-yl)aceticacid;GLPLDJICXMMSBB-UHFFFAOYSA-N;AKOS025116776;SB48783;DB-117109;G47276;EN300-1723715;Z1505695806;(3-tert-Butoxycarbonylamino-2-oxo-piperidin-1-yl)-acetic acid;(S)-2-(3-Tert-butoxycarbonylamino-2-oxopiperidin-1-yl)acetic acid;2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)aceticacid

Suppliers and Price of 2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
2-(3-((Tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)aceticacid
100mg
$ 247.00

Total 2 raw suppliers

Chemical Property of 2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:272.13722174
Heavy Atom Count:19
Complexity:375

Purity/Quality:

95+% ^*data from raw suppliers

2-(3-((Tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)aceticacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1CCCN(C1=O)CC(=O)O

Technology Process of 2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid

There total 7 articles about 2-(3-((tert-Butoxycarbonyl)amino)-2-oxopiperidin-1-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 99707-38-7,1256385-95-1
(+/-)-1-<(benzyloxycarbonyl)methyl>-3-<(tert-butoxycarbonyl)amino>-2-piperidone

: 733049-29-1
(+/-)-1-(carboxymethyl)-3-<(tert-butoxycarbonyl)amino>-2-piperidone

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; for 16h;

Reference yield: 86.0%

: ethyl 2-(3-((tert-butoxycarbonyl)amine)-2-oxopiperidin-1-yl)acetate

: 733049-29-1
(+/-)-1-(carboxymethyl)-3-<(tert-butoxycarbonyl)amino>-2-piperidone

Guidance literature:: ethyl 2-(3-((tert-butoxycarbonyl)amine)-2-oxopiperidin-1-yl)acetate; With potassium carbonate; In ethanol; water; at 20 ℃; pH=12;

With hydrogenchloride; In ethanol; water; pH=3;
DOI:10.2174/15701808113109990028

Reference yield:

: 99780-98-0
(+/-)-3-<(tert-butoxycarbonyl)amino>-2-piperidone

: 733049-29-1
(+/-)-1-(carboxymethyl)-3-<(tert-butoxycarbonyl)amino>-2-piperidone

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / NaH / dimethylformamide; tetrahydrofuran / 3.5 h / Ambient temperature

2: H₂ / 10percent Pd/C / methanol; H₂O / 2068.6 Torr

With hydrogen; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00152a014