O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid

Base Information

• Chemical Name: O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid
• CAS No.: 1320357-66-1
• Molecular Formula: C₁₈H₁₉NO₅
• Molecular Weight: 329.353
• Mol file: 1320357-66-1.mol

Synonyms:O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid

Chemical Property of O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid

There total 2 articles about O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-ethoxy-3-methoxybenzoil chloride (3535-36-2) + N-Phenylacetohydroxamic acid (1795-83-1) → O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid (1320357-66-1)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12.0833h;

DOI:10.1016/j.tet.2011.03.049

Reference yield:

N-Phenylhydroxylamine (100-65-2) → O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid (1320357-66-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / dichloromethane / 0 °C

2: triethylamine / dichloromethane / 12.08 h / 0 - 20 °C

With sodium hydrogencarbonate; triethylamine; In dichloromethane;

DOI:10.1016/j.tet.2011.03.049

Reference yield:

O-(4-ethoxy-3-methoxybenzoyl)-N-phenyl-acetohydroxamic acid (1320357-66-1) → 4-ethoxy-3-methoxybenzoic acid (3535-30-6) + Acetanilid (103-84-4)

Guidance literature:

With water; In methanol; for 0.833333h; UV-irradiation;

DOI:10.1016/j.tet.2011.03.049

upstream raw materials:

4-ethoxy-3-methoxybenzoil chloride

N-Phenylacetohydroxamic acid

N-Phenylhydroxylamine

Downstream raw materials:

4-ethoxy-3-methoxybenzoic acid

Acetanilid