O-[2-Deoxy-2-[3(R)-(tetradecanoyloxy)tetradecanoylamino]-beta-D-glucopyranosyl]-N-(tetradecanoyl)-L-seryl-beta-alanine

Base Information

• Chemical Name: O-[2-Deoxy-2-[3(R)-(tetradecanoyloxy)tetradecanoylamino]-beta-D-glucopyranosyl]-N-(tetradecanoyl)-L-seryl-beta-alanine
• CAS No.: 197663-09-5
• Molecular Formula: C₅₄H₁₀₁N₃O₁₂
• Molecular Weight: 984.409
• Mol file: 197663-09-5.mol

Synonyms:N-tetradecanoyl-O-<2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine

Chemical Property of O-[2-Deoxy-2-[3(R)-(tetradecanoyloxy)tetradecanoylamino]-beta-D-glucopyranosyl]-N-(tetradecanoyl)-L-seryl-beta-alanine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-[2-Deoxy-2-[3(R)-(tetradecanoyloxy)tetradecanoylamino]-beta-D-glucopyranosyl]-N-(tetradecanoyl)-L-seryl-beta-alanine

There total 11 articles about O-[2-Deoxy-2-[3(R)-(tetradecanoyloxy)tetradecanoylamino]-beta-D-glucopyranosyl]-N-(tetradecanoyl)-L-seryl-beta-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

N-tetradecanoyl-O-<3,4,6-tri-O-acetyl-2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine (197663-32-4) → N-tetradecanoyl-O-<2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine (197663-09-5)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; methanol; for 20h; Ambient temperature;

DOI:10.1248/cpb.45.1544

Reference yield: 74.0%

N-tetradecanoyl-O-<3,4,6-tri-O-acetyl-2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine (197663-32-4) → N-tetradecanoyl-O-<2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine (197663-09-5) + 3-{(S)-3-[(2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-3-((R)-3-hydroxy-tetradecanoylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionylamino}-propionic acid

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 20h;

DOI:10.1248/cpb.48.32

Reference yield: 5.0%

N-tetradecanoyl-O-[4,6-di-O-acetyl-2-deoxy-3-O-tetradecanoyl-2-[(R)-3-tetradecanoyloxytetradecanoylamino]-β-D-glucopyranosyl]-L-seryl-β-alanine (263010-71-5) → N-tetradecanoyl-O-<2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine (197663-09-5) + 3-{(S)-3-[(2R,3R,4R,5S,6R)-4,5-Dihydroxy-6-hydroxymethyl-3-((R)-3-hydroxy-tetradecanoylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionylamino}-propionic acid + N-tetradecanoyl-O-[2-deoxy-3-O-tetradecanoyl-2-[(R)-3-tetradecanoyloxytetradecanoylamino]-β-D-glucopyranosyl]-L-seryl-β-alanine

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 20h;

DOI:10.1248/cpb.48.32

upstream raw materials:

N-tetradecanoyl-O-<3,4,6-tri-O-acetyl-2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine

N-tetradecanoyl-O-[4,6-di-O-acetyl-2-deoxy-3-O-tetradecanoyl-2-[(R)-3-tetradecanoyloxytetradecanoylamino]-β-D-glucopyranosyl]-L-seryl-β-alanine

(R)-3-(dodecanoyloxy)tetradecanoic acid

N-tetradecanoyl-O-[3,4,6-tri-O-acetyl-2-deoxy-2-[(R)-3-tetradecanoyloxytetradecanoylamino]-β-D-glucopyranosyl]-L-serine

Downstream raw materials:

N-tetradecanoyl-O-<2-deoxy-2-<(R)-3-tetradecanoyloxytetradecanoylamino>-β-D-glucopyranosyl>-L-seryl-β-alanine p-nitrophenyl ester