Solifenacin N-Oxide

Base Information

• Chemical Name: Solifenacin N-Oxide
• CAS No.: 180272-28-0
• Molecular Formula: C23H26 N2 O3
• Molecular Weight: 378.471
• Mol file: 180272-28-0.mol

Synonyms:(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Oxido-1-azabicyclo[2.2.2]oct-3-yl Ester;Solifenacin N-Oxide

Chemical Property of Solifenacin N-Oxide

Chemical Property:

• PSA: 64.63000
• LogP: 3.98840
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly, Heated), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Solifenacin N-oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Solifenacin (S676700) .

Technology Process of Solifenacin N-Oxide

There total 1 articles about Solifenacin N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

solifenacin (242478-37-1,180272-14-4) → (1'S,3R)-3-[[(1'-phenyl-1',2',3',4'-tetrahydro-2'-isoquinolyl)carbonyl]oxy]quinuclidine 1-oxide (180272-28-0)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 10 - 20 ℃; for 1h;

upstream raw materials:

solifenacin