(Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one

Base Information

• Chemical Name: (Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one
• CAS No.: 1025784-74-0
• Molecular Formula: C₂₂H₁₉NO
• Molecular Weight: 313.399
• Mol file: 1025784-74-0.mol

Synonyms:(Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one

Chemical Property of (Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one

There total 2 articles about (Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

aniline (62-53-3) + 1-phenyl-3-(4-methylphenyl)prop-2-yn-1-one (14939-05-0) → (Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one (1025784-74-0)

Guidance literature:

at 80 ℃; for 1h;

DOI:10.1080/00397910801914343

Reference yield: 81.0%

(Z)-3-amino-1-phenyl-3-(4-methylphenyl)-prop-2-en-1-one (52939-90-9) + phenylboronic acid (98-80-6) → (Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one (1025784-74-0)

Guidance literature:

With copper diacetate; triethylamine; In 1,2-dichloro-ethane; at 50 ℃; for 24h;

DOI:10.1016/j.tetlet.2018.10.030

Reference yield: 93.0%

(Z)-3-(4-methylphenyl)-1-phenyl-3-(phenylamino)prop-2-en-1-one (1025784-74-0) → 5-(4-methylphenyl)-1-phenyl-1H-1,2,3-triazole (68809-45-0)

Guidance literature:

With 4-toluenesulfonyl azide; lithium tert-butoxide; In dichloromethane; at 20 ℃; regiospecific reaction;

DOI:10.1002/anie.201307499

upstream raw materials:

aniline

1-phenyl-3-(4-methylphenyl)prop-2-yn-1-one

(Z)-3-amino-1-phenyl-3-(4-methylphenyl)-prop-2-en-1-one

phenylboronic acid

Downstream raw materials:

5-(4-methylphenyl)-1-phenyl-1H-1,2,3-triazole