N-(2-CARBOXYBENZOYL)-(-)-10,2-CAMPHORSULTAM

Base Information

• Chemical Name: N-(2-CARBOXYBENZOYL)-(-)-10,2-CAMPHORSULTAM
• CAS No.: 179950-32-4
• Molecular Formula: C18H21 N O5 S
• Molecular Weight: 363.43
• Hs Code.: 2934999090
• Mol file: 179950-32-4.mol

Synonyms:Benzoicacid, 2-[(tetrahydro-8,8-dimethyl-2,2-dioxido-3H-3a,6-methano-2,1-benzisothiazol-1(4H)-yl)carbonyl]-,[3aS-(3aa,6a,7ab)]-

Chemical Property of N-(2-CARBOXYBENZOYL)-(-)-10,2-CAMPHORSULTAM

Chemical Property:

• Melting Point: 181.0 to 185.0 °C
• Refractive Index: 1.659
• Boiling Point: 552.3±52.0 °C(Predicted)
• PKA: 3.17±0.36(Predicted)
• PSA: 100.13000
• Density: 1.45±0.1 g/cm3(Predicted)
• LogP: 3.38400
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(2-Carboxybenzoyl)-(-)-10,2-camphorsultam ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-CARBOXYBENZOYL)-(-)-10,2-CAMPHORSULTAM

There total 1 articles about N-(2-CARBOXYBENZOYL)-(-)-10,2-CAMPHORSULTAM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phthalic anhydride (85-44-9) + (2R)-bornane-10,2-sultam (94594-90-8,124224-04-0) → (1S,5R,7R)-4-(2-carboxybenzoyl)-3-thia-4-azatricyclo<5.2.1.01,5>decane 3,3-dioxide (179950-32-4)

Guidance literature:

With sodium hydride; Yield given; Multistep reaction; 1) C₆H₆, room temperature, 30 min, 2) C₆H₆, 40 min;

DOI:10.1246/bcsj.71.2715

Reference yield:

3,4,4-trimethyl-3-vinyl-hept-6-en-1-ol (1441048-48-1) + (1S,5R,7R)-4-(2-carboxybenzoyl)-3-thia-4-azatricyclo<5.2.1.01,5>decane 3,3-dioxide (179950-32-4) → (S)-3,4,4-trimethyl-3-vinylhept-6-en-1-yl 2-((3aR,6R)-8,8-dimethyl-2,2-dioxidohexahydro-3H-3a,6-methanobenzo[c] isothiazole-1-carbonyl)benzoate + (R)-3,4,4-trimethyl-3-vinylhept-6-en-1-yl 2-((3aR,6R)-8,8-dimethyl-2,2-dioxidohexahydro-3H-3a,6-methanobenzo[c]isothiazole-1-carbonyl)benzoate

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 25 ℃; for 24h;

Reference yield:

3,4,4-trimethyl-3-vinyl-hept-6-en-1-ol (1441048-48-1) + (1S,5R,7R)-4-(2-carboxybenzoyl)-3-thia-4-azatricyclo<5.2.1.01,5>decane 3,3-dioxide (179950-32-4) → C30H41NO5S (1441048-50-5) + C30H41NO5S (1441048-52-7)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo400491n

upstream raw materials:

phthalic anhydride

(2R)-bornane-10,2-sultam

Downstream raw materials:

C₃₀H₄₁NO₅S

C₃₀H₄₁NO₅S

Refernces